PROTEOMICS IN NON-HUMAN PRIMATES: UTILIZING RNA-SEQ DATA TO IMPROVE PROTEIN IDENTIFICATION BY MASS SPECTROMETRY IN VERVET MONKEYS

Proteomics in non-human primates: utilizing RNA-Seq data to improve protein identification by mass spectrometry in vervet monkeys

Abstract Background Shotgun proteomics utilizes a database search strategy to compare detected mass spectra to a library of theoretical spectra derived from reference genome information.As such, the robustness of proteomics results is contingent upon the completeness and accuracy of the gene annotation in the reference genome.For animal models of d

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Mechanical positioning of multiple nuclei in muscle cells.

Many types of large cells have multiple nuclei.In skeletal muscle fibers, the nuclei are distributed along the cell to maximize their internuclear distances.This myonuclear positioning is crucial for cell function.Although microtubules, microtubule associated proteins, and motors have been implicated, mechanisms responsible for myonuclear positioni

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Role of physiotherapy interventions in treating varicose veins

The lower limb venous system is responsible for returning blood from the foot, leg, and thigh toward the heart.Chronic venous disease occurs by an inability of the blood to completely return due to structural or functional abnormalities of the veins of the lower limbs.Varicose Viewfinder veins are enlarged veins that have become tortious and abnorm

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